Side effects of denamarin

I have been getting many hits on this site on possible side effects to denamarin. Denamarin is a combination of Sylimarin (milk thistle) and SAMe. Denamarin is considered extremely safe if administered in the recommended dosage. One important point to make is it should be administered on an empty stomach. It has been known to cause diarrhea in some cases. SAMe can cause some dogs to vomit. But you can switch, with the advice of your vet, to standard milk thistle, liquid vitamin E and a B complex with C. The E and C enhance the effects of the milk thistle. I have taken Macy off Denamarin. Not that she was having problems with the medication, but she was doing beautifully on the milk thistle plus vitamins. She had come completely out of jaundice, was eating well and had regained all her weight. I must add it is cheaper to make your own denamarin. Here is what she gets. One 500 milligram milk thistle 2x a day, One 200 IU vitamin E soft gel (you can also find this in liquid form at a good health food store) 1x a day, Vitamin B complex with C (make sure this includes at least 50 milligrams of B12) 1x a day. You can pick the dosage you want. I tend to get the highest, 1000 milligrams. Vitamin K, 100 milligrams, 1x a day before bedtime. The vet had prescribed 50 milligrams, but the pills are tiny and impossible to cut in half. I upped the ante and watched her carefully. She has done just fine on the higher dosage. Again, I must emphasize that SAMe and vitamin E are not the same. SAMe is a biochemical produced by amino acids and used specifically for liver disease. Vitamin E is a supplement that enhances the effects of milk thistle. Partner with your vet before you make the switch and closely monitor the results. If you are noticing side effects to denamarin, vomiting and diarrhea are most common, make sure you are administering the medication on an empty stomach first. If that does not help, then ask your vet if you might try the above substitute I have found milk thistle to be tremendously effective in Macy’s improved health. But the addition of vitamin B, C and E were important too. For more on that read here. I must encourage bookmarking this site for any questions on pet health or medications. They have a wealth of information in their library that is very user friendly. The other thing I like about their site is it is very balanced in it’s opinion. Whenever I have a question, they are my first source of reference. Bookmark it, flag it or make me really happy and make it your home page. Merry Christmas to you all! Got lots coming up in the next few weeks, so stay tuned. We are addressing traditional heartworm and flea medications, the study just published in New Zealand on the global impact of pets and discussing more of the searches that land you on my page…successfully or unsuccessfully. This all takes a bit of work, but stay tuned. I really enjoy your feedback, so please don’t be shy! Happy Holidays and all the best for the new year! Margot Hackett